Early Detection Research Network

ACTR3

Aliases:
This biomarker is also known as:
  • Actin-like protein 3,
  • actin-related protein 3,
  • ARP3 (actin-related protein 3, yeast) homolog,
  • actin-like protein 3,
  • P61158,
  • ARP3,
  • ARP3 actin-related protein 3 homolog (yeast),
  • ACTR3,

Description…

The ACTR3 protein is a component of the ARP2/3 complex, which is essential to cell shape and motility.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: ACTR3

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

ACTR3 is a tumor vascular marker (TVM) identified through expression profiling of ovarian cancer vascular cells.

Performance Comment

In PMID:21617380, 13 tumor vascular markers (TVMs) from 50 candidates identified through expression profiling of ovarian cancer vascular cells and selected to be either transmembrane or secreted, and to be either absent or expressed at low levels in normal tissues while overexpressed in tumors, based on analysis of 1,110 normal and tumor tissues from publicly available Affymetrix microarray data were investigated. ACTR3 was not selected to be studied further.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.