Early Detection Research Network

ADH5

Aliases:
This biomarker is also known as:
  • ADH-3,
  • alcohol dehydrogenase class-III,
  • alcohol dehydrogenase class-3,
  • EC 1.1.1.1,EC 1.1.1.-,EC 1.1.1.284,
  • Alcohol dehydrogenase 5,
  • glutathione-dependent formaldehyde dehydrogenase,
  • FDH,
  • GSNOR,
  • Alcohol dehydrogenase class-III,
  • GSH-FDH,
  • ADH5,
  • Glutathione-dependent formaldehyde dehydrogenase,
  • FALDH,
  • alcohol dehydrogenase (class III), chi polypeptide,
  • ADHX,
  • alcohol dehydrogenase 5 (class III), chi polypeptide,
  • S-(hydroxymethyl)glutathione dehydrogenase,
  • alcohol dehydrogenase class chi chain,
  • Alcohol dehydrogenase class chi chain,
  • formaldehyde dehydrogenase,

Description…

ADH5 is a member of the alcohol dehydrogenase family. This protein forms a homodimer. ADH5 is ineffective in oxidizing ethanol, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. There are several non-transcribed pseuodogenes related to this gene.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: ADH5

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

ADH5 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.