Early Detection Research Network

AKR1C2

Aliases:
This biomarker is also known as:
  • DDH2,
  • chlordecone reductase homolog HAKRD,
  • AKR1C-pseudo,
  • MCDR2,
  • 3-alpha-HSD3,
  • Chlordecone reductase homolog HAKRD,
  • DD,
  • Dihydrodiol dehydrogenase 2,
  • dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III,
  • SRXY8,
  • type III,
  • Dihydrodiol dehydrogenase/bile acid-binding protein,
  • dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase,
  • HAKRD,
  • HBAB,
  • Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase,
  • aldo-keto reductase family 1, member C2,
  • DD/BABP,
  • Type III 3-alpha-hydroxysteroid dehydrogenase,
  • BABP,
  • AKR1C2,
  • aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III),
  • aldo-keto reductase family 1 member C2,
  • DD-2,
  • trans-1,2-dihydrobenzene-1,2-diol dehydrogenase,
  • type II dihydrodiol dehydrogenase,
  • DD2,
  • pseudo-chlordecone reductase,

Description…

From NCBI Gene: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: AKR1C2

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.