Breast

ANO1 is located within the 11q13 amplicon, one of the most frequently amplified chromosomal regions in human cancer. ANO1 is amplified and highly expressed in breast cancer cell lines and primary tumors.

Identifier RDF Subject URI of this object

QA State The current status with regard to quality assurance of this object.

Phase The current phase of the biomarker's development with regard to this organ.

Protocols Protocols (and studies) that are studying this object.

Publications Publications that have been written discussing this object.

Resources Additional resources about this object.

Datasets Datasets providing measured scientific bases for this biomarker.

Performance Comment A short summary of the biomarker performance with respect to a specific organ

Organ The organ for which the biomarker indicates diseases.

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FDA Certification

Contents

Triple Negative Breast Cancer Team Project

Triple negative breast cancers (TNBC), comprise 15-20% of breast cancers, and are associated with later stage at diagnosis, increased mortality, and occur more frequently in younger women where mammographic screening is less reliable. TNBCs are more likely to be diagnosed by physical exam than by mammographic screening. There is an unmet clinical need for biomarkers for the early detection of TNBC. Here, we are proposing the development of a plasma-based biomarker panel for the routine screening of women over the age of 40 for TNBC that can be used to identify women for further imaging.