Early Detection Research Network

APCS

Aliases:
This biomarker is also known as:
  • amyloid P component, serum,
  • Serum amyloid P-component,
  • PTX2,
  • 9.5S alpha-1-glycoprotein,
  • APCS,
  • pentaxin-related,
  • MGC88159,
  • SAP,

Description…

APCS, a secreted glycoprotein found in serum and urine, interacts with DNA and histones and may scavenge nuclear material released from damaged circulating cells. It is thought to control the degradation of chromatin and has been demonstrated to bind to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. APCS may also function as a calcium-dependent lectin. APCS is a member of the pentaxin family of proteins, which characteristically bind two calcium ions per subunit and have a a discoid arrangement of 5 non-covalently bound subunits.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: APCS

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.