Early Detection Research Network

Ovary

B2M has been shown to be the target molecule of an antibody pool against SKOV3 ovarian cancer cells. Studies have also indicated that specific antibody of B2M can inhibit the growth of SKOV3. In addition, overexpression of B2M promotes the growth of SKOV3 cells in vitro.
http://edrn.jpl.nasa.gov/bmdb/biomarkers/organs/74/92
Curated
Three
Of the 28 ovarian cancer biomarkers tested in prediagnostic specimens, from the PLCO, CA125 remains the single best biomarker for ovarian cancer and has its strongest signal within six months of diagnosis. B2M alone was not a strong predictor.
22e8d394562348d4a780822980f5add9
no
no
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