Early Detection Research Network

BCL2L2

Aliases:
This biomarker is also known as:
  • KIAA0271,
  • protein phosphatase 1, regulatory subunit 51,
  • BCL2-L-2,
  • BCLW,
  • BCL2-like 2,
  • regulatory subunit 51,
  • BCL-W,
  • Apoptosis regulator Bcl-W,
  • Bcl2-L-2,
  • bcl-2-like protein 2,
  • apoptosis regulator BCL-W,
  • protein phosphatase 1,
  • PPP1R51,

Description…

From NCBI Gene: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State 3: Under Review
Type: Protein
Short Name:
HGNC Name 3: BCL2L2

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.