Early Detection Research Network

BLVRB

Aliases:
This biomarker is also known as:
  • BLVRB,
  • FR,
  • Green heme-binding protein,
  • BVRB,
  • Biliverdin-IX beta-reductase,
  • BVR-B,
  • short chain dehydrogenase/reductase family 43U, member 1,
  • FLR,
  • NADPH-dependent diaphorase,
  • MGC117413,
  • NADPH-flavin reductase,
  • Flavin reductase,
  • Biliverdin reductase B,
  • GHBP,
  • SDR43U1,
  • biliverdin reductase B (flavin reductase (NADPH)),

Description…

BLVRB, a cytoplasmic protein, is a broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and pyrroloquinoline quinone. It contributes to heme catabolism and metabolizes linear tetrapyrroles. BLVRB can also reduce the complexed Fe3+ iron to Fe2+ in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin. BLVRB is predominantly expressed in liver and erythrocytes, and at lower levels in heart, lung, adrenal gland and cerebrum.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: BLVRB

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.