Early Detection Research Network

BPIFA1

Aliases:
This biomarker is also known as:
  • NASG,
  • LUNX,
  • Lung-Specific Protein X,
  • BA49G10.5,
  • Ligand-Binding Protein RYA3,
  • BPIFA1,
  • SPLUNC1,
  • Nasopharyngeal Carcinoma-Related Protein,
  • Palate Lung And Nasal Epithelium Clone Protein,
  • Palate, Lung And Nasal Epithelium Associated,
  • Tracheal Epithelium Enriched Protein,
  • Tracheal Epithelium-Enriched Protein,
  • Palate, Lung And Nasal Epithelium Carcinoma Associated,
  • PLUNC,
  • BPI Fold Containing Family A, Member 1,
  • BPI Fold-Containing Family A Member 1,
  • SPURT,
  • Secretory Protein In Upper Respiratory Tracts,
  • Von Ebner Protein Hl,
  • Protein Plunc,

Description…

The BPIFA1 gene was formerly known as PLUNC. This human gene is the homolog of murine Plunc, and shows the same expression pattern as murine Plunc. Both are expressed in the upper airways and nasopharyngeal regions. Human BPIFA1 may be involved in the airway inflammatory response after exposure to irritants and may be associated with tumor progression. BPIFA1 may also play a role in innate immune responses of the upper airways. And it may serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but only three full length variants have been isolated.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: BPIFA1

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.