Early Detection Research Network


This biomarker is also known as:
  • cutaneous T-cell attracting chemokine,
  • C-C motif chemokine 27,
  • ESkine,
  • SCYA27,
  • skinkine,
  • Cutaneous T-cell-attracting chemokine,
  • small inducible cytokine subfamily A (Cys-Cys), member 27,
  • Skinkine,
  • CCL27,
  • IL-11 R-alpha-locus chemokine,
  • CTAK,
  • IL-11 Ralpha-locus chemokine,
  • cutaneous T-cell-attracting chemokine,
  • ALP,
  • PESKY,
  • chemokine (C-C motif) ligand 27,
  • CC chemokine ILC,
  • small-inducible cytokine A27,
  • CTACK,
  • ILC,
  • Small-inducible cytokine A27,


CCL27 is a member of the CC cytokine family, and is involved in immunoregulatory and inflammatory processes. CC cytokines are characterized by two adjacent cysteines. CCL27 functions as a chemotactic factor that attracts skin-associated memory T-lymphocytes. CCL27 may also play a role in mediating homing of lymphocytes to cutaneous sites. CCL27 binds specifically to chemokine receptor 10 (CCR10).


There are no datasets associated with this biomarker.

QA State: Curated
Type: Protein
HGNC Name: CCL27

The following organs have data associated with this biomarker…


Phase: Two
QA State: Under Review


CCL27 was present at higher levels among cases compared to controls with reasonable AUC values.

Performance Comment

CCL27 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.