Early Detection Research Network

CCL28

Aliases:
This biomarker is also known as:
  • C-C motif chemokine 28,
  • Mucosae-associated epithelial chemokine,
  • Small-inducible cytokine A28,
  • Protein CCK1,
  • small-inducible cytokine A28,
  • small inducible cytokine subfamily A (Cys-Cys), member 28,
  • MEC,
  • chemokine (C-C motif) ligand 28,
  • chemokine (C-C motif) ligand 28 splice variant chi,
  • mucosae-associated epithelial chemokine,
  • SCYA28,
  • CC chemokine CCL28,
  • CCK1,
  • small inducible cytokine A28,

Description…

CCL28 is a member of the small cytokine CC subfamily, and is involved in immunoregulatory and inflammatory processes. CC cytokines are characterized by two adjacent cysteines. CCL28 functions as a chemotactic factor for resting CD4 or CD8 T cells and eosinophils. CCL28 binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State 3: Curated
Type: Protein
Short Name:
HGNC Name 3: CCL28

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

CCL28 was present at higher levels among cases compared to controls with reasonable AUC values.

Performance Comment

CCL28 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.