Early Detection Research Network

CCND1

Aliases:
This biomarker is also known as:
  • CCND1,
  • cyclin D1 (PRAD1: parathyroid adenomatosis 1),
  • cyclin D1,
  • PRAD1 oncogene,
  • G1/S-specific cyclin-D1,
  • B-cell lymphoma 1 protein,
  • BCL-1,
  • BCL1,
  • BCL-1 oncogene,
  • U21B31,
  • PRAD1,
  • D11S287E,
  • B-cell CLL/lymphoma 1,

Description…

CCND1 is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. CCND1 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: CCND1

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

CCND1 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.