Early Detection Research Network

DGCR6

Aliases:
This biomarker is also known as:
  • protein DGCR6,
  • DiGeorge syndrome critical region gene 6,
  • DiGeorge syndrome critical region 6,
  • DGCR6,
  • DiGeorge syndrome critical region protein 6,

Description…

DGCR6 is located on chromosome 22q11.21. Microdeletions in this region are associated with DiGeorge syndrome, and more widely, the CATCH 22 syndrome. DGCR6, also known as DiGeorge syndrome critical region 6, is thought to be involved in DiGeorge syndrome pathology and in schizophrenia. Another function attributed to this gene is a role in neural crest cell migration into the third and fourth pharyngeal pouches. The DGCR6 protein shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: DGCR6

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

DGCR6 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.