Early Detection Research Network

ELF2

Aliases:
This biomarker is also known as:
  • NERF-1A,
  • NERF-1B,
  • NERF-2,
  • ETS-related transcription factor Elf-2,
  • EU32,
  • ELF2,
  • New ETS-related factor,
  • E74-like factor 2 (ets domain transcription factor),
  • NERF-1a,b,
  • E74-like factor 2,
  • ets family transcription factor ELF2C,
  • NERF,
  • new Ets-related factor,

Description…

ELF2 is a nuclear protein that is conserved across several species. Multiple isoforms have been identified. Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter, while isoform 2 is thought to function in repression of RUNX1-mediated transactivation.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: ELF2

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

ELF2 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.