Early Detection Research Network

EPB41L3

Aliases:
This biomarker is also known as:
  • DAL1,
  • differentially expressed in adenocarcinoma of the lung protein 1,
  • erythrocyte membrane protein band 4.1-like 3,
  • KIAA0987,
  • EPB41L3,
  • band 4.1-like protein 3,
  • DAL-1,
  • 4.1B,
  • Differentially expressed in adenocarcinoma of the lung protein 1,
  • Q9Y2J2,

Description…

EPB41L3 protein is a critical growth regulator in the pathogenesis of meningiomas. There are three isoforms of this protein, produced by alternative splicing.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: EPB41L3

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

EPB41L3 has been identified as a functional suppressor of epithelial ovarian cancers.

Performance Comment

EPB41L3 was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. EPB41L3 was not in the group of 13 selected for further validation.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.