Early Detection Research Network

ERCC4

Aliases:
This biomarker is also known as:
  • XPF,
  • excision-repair, complementing defective, in Chinese hamster,
  • ERCC4,
  • excision repair cross-complementing rodent repair deficiency, complementation group 4,
  • RAD1,
  • DNA repair endonuclease XPF,
  • DNA repair protein complementing XP-F cells,
  • Xeroderma pigmentosum group F-complementing protein,
  • xeroderma pigmentosum group F-complementing protein,
  • DNA excision repair protein ERCC-4,
  • xeroderma pigmentosum, complementation group F,
  • ERCC11,
  • EC 3.1.-.-,

Description…

ERCC4 is a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. It forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. Mutations in the ERCC4 gene can cause xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: ERCC4

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.