Early Detection Research Network

ERG

Aliases:
This biomarker is also known as:
  • Transcriptional Regulator ERG,
  • Erg,
  • V-Ets Erythroblastosis Virus E26 Oncogene Like,
  • Ets-Related,
  • V-Ets Avian Erythroblastosis Virus E26 Oncogene Related,
  • P55,
  • Transcriptional Regulator ERG (Transforming Protein ERG),
  • V-Ets Erythroblastosis Virus E26 Oncogene Homolog (Avian),
  • ERG,
  • TMPRSS2/ERG Fusion,
  • V-Ets Erythroblastosis Virus E26 Oncogene Like (Avian),
  • Transforming Protein ERG,

Description…

The ERG gene codes for the ERG protein, a transcription factor that is a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. Members of this family are involved in embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. ERG is mainly expressed in the nucleus. ERG is also involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Different isoforms arising from multiple alternatively spliced transcripts have been identified.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: ERG

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.