Early Detection Research Network

EYA4

Aliases:
This biomarker is also known as:
  • Eyes Absent-Like Protein 4,
  • CMD1J,
  • Eyes Absent Homolog 4 (Drosophila),
  • EYA Transcriptional Coactivator And Phosphatase 4,
  • Eyes Absent (Drosophila) Homolog 4,
  • DJ78N10.1 (Eyes Absent),
  • EC 3.1.3.48,
  • Eyes Absent Homolog 4,
  • DFNA10,
  • EYA4,

Description…

From NCBI Gene: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development, and for continued function of the mature organ of Corti. Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus. The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack. Defects in this gene are also associated with dilated cardiomyopathy 1J. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Proteomic
HGNC Name:

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.