Early Detection Research Network

Ovary

APO-1/Fas receptor (FasR) is a cell surface receptor that, when activated, triggers apoptosis. It has been postulated that this receptor may be involved in the clearance of benign ovarian epithelial inclusion cysts (IC). An observed decreased expression of FasR in malignant ovarian epithelial neoplasms as compared with benign ovarian epithelial lesions suggests that a decreased sensitivity to Fas-mediated apoptosis may be involved in ovarian epithelial carcinogenesis.
http://edrn.jpl.nasa.gov/bmdb/biomarkers/organs/915/986
Under Review
Three
22e8d394562348d4a780822980f5add9
no
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