Early Detection Research Network


This biomarker is also known as:
  • four-jointed box protein 1,
  • four-jointed protein homolog,
  • four jointed box 1 (Drosophila),
  • putative secreted ligand homologous to fjx1,
  • Four-jointed protein homolog,
  • FLJ22416,
  • FLJ25593,
  • FJX1,
  • Q86VR8,


FJX1 is the human ortholog of mouse and Drosophila four-jointed gene product. The Drosophila protein is important for growth and differentiation of legs and wings, and for proper development of the eyes. It is predicted, based on similarity, that human FJX1 may act as an inhibitor of dendrite extension and branching.


There are no datasets associated with this biomarker.

QA State: Curated
Type: Protein

The following organs have data associated with this biomarker…


Phase: Two
QA State: Under Review


No additional ovarian data available.

Performance Comment

FJX1 was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. FJX1 was not in the group of 13 selected for further validation.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.