Early Detection Research Network

GCLM

Aliases:
This biomarker is also known as:
  • GLCLR,
  • Gamma-ECS regulatory subunit,
  • glutamate--cysteine ligase regulatory subunit,
  • glutamate-cysteine ligase regulatory protein,
  • GSC light chain,
  • Gamma-glutamylcysteine synthetase regulatory subunit,
  • gamma-glutamylcysteine synthetase,
  • gamma-ECS regulatory subunit,
  • Glutamate--cysteine ligase modifier subunit,
  • glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD),
  • glutamate-cysteine ligase modifier subunit delta2 alternative splicing,
  • gamma-glutamylcysteine synthetase regulatory subunit,
  • GCS light chain,
  • GCLM,
  • glutamate--cysteine ligase modifier subunit,
  • glutamate-cysteine ligase, modifier subunit,

Description…

From NCBI Gene: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: GCLM

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.