Early Detection Research Network

GFPT1

Aliases:
This biomarker is also known as:
  • Hexosephosphate aminotransferase 1,
  • GFPT,
  • Glutamine:fructose 6 phosphate amidotransferase 1,
  • D-fructose-6-phosphate amidotransferase 1,
  • Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1,
  • GFAT 1,
  • GFPT1,
  • glutamine--fructose-6-phosphate transaminase 1,
  • GFAT1m,
  • GFA,
  • GFAT1,
  • GFAT,

Description…

GFPT1 is the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. It appears to catalyze the formation of glucosamine 6-phosphate. It may also be involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. GFPT1 is predominantly expressed in skeletal muscle, selectively expressed in striated muscle, and not expressed in brain.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: GFPT1

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.