Early Detection Research Network

HAPLN1

Aliases:
This biomarker is also known as:
  • Proteoglycan link protein,
  • LP,
  • cartilage linking protein 1,
  • Cartilage link protein,
  • Hyaluronan and proteoglycan link protein 1 [Precursor],
  • HAPLN1,
  • CRTL1,
  • HPLN1,

Description…

This widely expressed protein stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: HAPLN1

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Under Review

Overview

Detected via microarray expression.

Performance Comment

Attributes

Phase: One
QA State: Under Review

Overview

No additional ovarian data available.

Performance Comment

HAPLN1 was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. HAPLN1 was not in the group of 13 selected for further validation.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.