Early Detection Research Network


This biomarker is also known as:
  • estrogen down-regulated gene 1 protein,
  • HIS1,
  • hexamethylene-bis-acetamide-inducible transcript 1,
  • CLP-1,
  • hexamethylene bisacetamide-inducible protein,
  • hexamthylene bis-acetamide inducible 1,
  • menage a quatre protein 1,
  • hexamethylene bis-acetamide-inducible protein 1,
  • Menage a quatre protein 1,
  • cardiac lineage protein 1,
  • HEXIM1,
  • Estrogen down-regulated gene 1 protein,
  • CLP1,
  • HMBA-inducible,
  • menage a quatre 1,
  • MAQ1,
  • Cardiac lineage protein 1,
  • EDG1,
  • hexamethylene bis-acetamide inducible 1,
  • protein HEXIM1,
  • Hexamethylene bis-acetamide-inducible protein 1,


HEXIM1 is an intronless transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. HEXIM1 expression is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells.


There are no datasets associated with this biomarker.

QA State: Curated
Type: Protein

The following organs have data associated with this biomarker…


Phase: Two
QA State: Under Review


No additional breast data available.

Performance Comment

HEXIM1 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.