Early Detection Research Network

Prostate

http://edrn.jpl.nasa.gov/bmdb/biomarkers/organs/684/608
Curated
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Significance Analysis of Microarray (SAM) was used to develop a 7-gene classifier. The overall prediction accuracy and sensitivity is 71% and 76%, respectively. The inclusion of the Gleason sum to the seven-gene classifier raised the prediction accuracy and sensitivity to 83% and 76% respectively This prognostic signature is closely associated with biochemical recurrence in patients after radical prostatectomy. The seven genes are: RRAGD, PQBP1, HIST1H2BC (HIST1H2BE, HIST1H2BF, HIST1H2BI), ALDH1A2, TRIM22, RBPMS, HSPB8.
609af3b1485945828291cf719af8ac9f
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