Early Detection Research Network


This biomarker is also known as:
  • 3-hydroxyacyl-CoA dehydrogenase type-2,
  • mental retardation, X-linked, syndromic 10,
  • Mitochondrial RNase P protein 2,
  • short chain dehydrogenase/reductase family 5C, member 1,
  • CAMR,
  • SDR5C1,
  • short chain type dehydrogenase/reductase XH98G2,
  • 3-hydroxyacyl-CoA dehydrogenase type II,
  • XH98G2,
  • mitochondrial ribonuclease P protein 2,
  • AB-binding alcohol dehydrogenase,
  • hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme A dehydrogenase, type II,
  • 17-beta-HSD 10,
  • Short-chain type dehydrogenase/reductase XH98G2,
  • endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • HADH2,
  • Mitochondrial ribonuclease P protein 2,
  • ABAD,
  • HSD17B10,
  • Type II HADH,
  • ERAB,
  • mitochondrial RNase P subunit 2,
  • DUPXp11.22,
  • MRXS10,
  • amyloid-beta peptide binding alcohol dehydrogenase,
  • HCD2,
  • MRX31,
  • hydroxysteroid (17-beta) dehydrogenase 10,
  • SCHAD,
  • MRPP2,
  • 17b-HSD10,
  • 17-beta-hydroxysteroid dehydrogenase 10,
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase,
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • MRX17,
  • MHBD,
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2,
  • EC,EC,


HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10, is a member of the short-chain dehydrogenase/reductase superfamily. HSD17B10 functions in mitochondrial tRNA maturation and catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein is thought to play a role in the development of Alzheimer's disease. There are several alternatively spliced transcript variants, of which only two have been fully sequenced.


There are no datasets associated with this biomarker.

QA State: Curated
Type: Protein
HGNC Name: HSD17B10

The following organs have data associated with this biomarker…


Phase: Two
QA State: Under Review


No additional breast data is available.

Performance Comment

HSD17B10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.