Early Detection Research Network

HSD17B10

Aliases:
This biomarker is also known as:
  • MHBD,
  • SDR5C1,
  • hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme A dehydrogenase, type II,
  • 3-hydroxyacyl-CoA dehydrogenase type-2,
  • HCD2,
  • ERAB,
  • mental retardation, X-linked, syndromic 10,
  • mitochondrial ribonuclease P protein 2,
  • MRX31,
  • ABAD,
  • Type II HADH,
  • 17-beta-hydroxysteroid dehydrogenase 10,
  • CAMR,
  • hydroxysteroid (17-beta) dehydrogenase 10,
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • AB-binding alcohol dehydrogenase,
  • MRX17,
  • mitochondrial RNase P subunit 2,
  • short chain type dehydrogenase/reductase XH98G2,
  • amyloid-beta peptide binding alcohol dehydrogenase,
  • Mitochondrial RNase P protein 2,
  • 17b-HSD10,
  • 17-beta-HSD 10,
  • SCHAD,
  • 3-hydroxyacyl-CoA dehydrogenase type II,
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2,
  • Mitochondrial ribonuclease P protein 2,
  • XH98G2,
  • endoplasmic reticulum-associated amyloid beta-peptide-binding protein,
  • EC 1.1.1.35,EC 1.1.1.178,
  • DUPXp11.22,
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase,
  • HADH2,
  • Short-chain type dehydrogenase/reductase XH98G2,
  • MRPP2,
  • MRXS10,
  • short chain dehydrogenase/reductase family 5C, member 1,

Description…

HSD17B10, hydroxysteroid (17-beta) dehydrogenase 10, is a member of the short-chain dehydrogenase/reductase superfamily. HSD17B10 functions in mitochondrial tRNA maturation and catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein is thought to play a role in the development of Alzheimer's disease. There are several alternatively spliced transcript variants, of which only two have been fully sequenced.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State 3: Curated
Type: Protein
Short Name:
HGNC Name 3: HSD17B10

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data is available.

Performance Comment

HSD17B10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.