Early Detection Research Network

IFI27

Aliases:
This biomarker is also known as:
  • IFI27,
  • Interferon alpha-induced 11.5 kDa protein,
  • Interferon alpha-inducible protein 27, mitochondrial,
  • ISG12(a),
  • ISG12,
  • P27,
  • interferon, alpha-inducible protein 27,
  • ISG12A,
  • p27,
  • FAM14D,
  • Interferon-stimulated gene 12a protein,

Description…

IFI27, a multi-pass membrane protein, promotes cell death. It mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9. IFI27 belongs to the IFI6/IFI27 family. It is up-regulated by interferons.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: IFI27

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.