Early Detection Research Network

IGFBP3

Aliases:
This biomarker is also known as:
  • growth hormone-dependent binding protein,
  • binding protein 29,
  • insulin-like growth factor binding protein 3,
  • IGF-binding protein 3,
  • IBP3,
  • binding protein 53,
  • BP-53,
  • acid stable subunit of the 140 K IGF complex,

Description…

The IGFBP3 gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a secreted protein with an IGFBP domain and a thyroglobulin type-I domain. IGFBP3 forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. It is expressed by most tissues. Present in plasma.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State 3: Under Review
Type: Protein
Short Name:
HGNC Name 3: IGFBP3

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.