Early Detection Research Network

KDR

Aliases:
This biomarker is also known as:
  • kinase insert domain receptor (a type III receptor tyrosine kinase),
  • FLK-1,
  • CD309 antigen,
  • Protein-tyrosine kinase receptor flk-1,
  • fetal liver kinase 1,
  • tyrosine kinase growth factor receptor,
  • soluble VEGFR2,
  • vascular endothelial growth factor receptor 2,
  • Fetal liver kinase 1,
  • fetal liver kinase-1,
  • CD309,
  • FLK1,
  • KDR,
  • VEGFR-2,
  • VEGFR,
  • protein-tyrosine kinase receptor Flk-1,
  • Kinase insert domain receptor,
  • VEGFR2,
  • EC 2.7.10.1,

Description…

From NCBI Gene: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: KDR

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.