Early Detection Research Network

Prostate

Kallikreins (KLKs) are highly conserved serine proteases that play key roles in a variety of physiological and pathological processes. KLK4 is regulated by androgens and is highly specific to prostate for expression. hK4 is intracellularly localized. KLK4 is predominantly expressed in the basal cells of the normal prostate gland and overexpressed in prostate cancer. hK4 has a unique structure and function compared with other members of the KLK family and may have a role in the biology and characterization of prostate cancer.
http://edrn.jpl.nasa.gov/bmdb/biomarkers/organs/57/78
Accepted
One
hK2, hK4 and hK11 do not distinguish cases from controls in these populations.
609af3b1485945828291cf719af8ac9f
no
no
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