Early Detection Research Network

KRAS

Aliases:
This biomarker is also known as:
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog,
  • c-Kirsten-ras protein,
  • K-ras p21 protein,
  • NS,
  • K-RAS2B,
  • NS3,
  • K-RAS2A,
  • cellular c-Ki-ras2 proto-oncogene,
  • KI-RAS,
  • KRAS2,
  • K-RAS4A,
  • KRAS,
  • K-RAS4B,
  • RASK2,
  • oncogene KRAS2,
  • Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog,
  • c-K-ras2 protein,
  • PR310 c-K-ras oncogene,
  • transforming protein p21,
  • C-K-RAS,
  • KRAS1,

Description…

The KRAS gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: KRAS

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.