Early Detection Research Network


This biomarker is also known as:
  • lymphocyte cytosolic protein 2,
  • 76 kDa tyrosine phosphoprotein,
  • SLP-76,
  • lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD),
  • SLP76,
  • SLP-76 tyrosine phosphoprotein,
  • LCP2,
  • SH2 domain-containing leukocyte protein of 76 kDa,
  • lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa),
  • SH2 domain-containing leukocyte protein of 76kD,


LCP2, previously known as SLP76, functions as an adaptor or scaffolding protein. LCP2 has three modular domains. The amino-terminal end has an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation. LCP2 also contains a central proline-rich domain and a COOH-terminal SH2 domain.


There are no datasets associated with this biomarker.

QA State: Curated
Type: Protein

The following organs have data associated with this biomarker…


Phase: Two
QA State: Under Review


No additional breast data is available.

Performance Comment

LCP2 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.