Early Detection Research Network

LGALS3BP

Aliases:
This biomarker is also known as:
  • galectin-3-binding protein,
  • Mac-2 BP,
  • MAC-2-BP,
  • 90K,
  • serum protein 90K,
  • L3 antigen,
  • BTBD17B,
  • basement membrane autoantigen p105,
  • tumor-associated antigen 90K,
  • Mac-2-binding protein,
  • Q08380,
  • mac-2 BP,
  • Basement membrane autoantigen p105,
  • lectin, galactoside-binding, soluble, 3 binding protein,
  • LGALS3BP,
  • lectin galactoside-binding soluble 3-binding protein,
  • Lectin galactoside-binding soluble 3-binding protein,
  • Tumor-associated antigen 90K,
  • MAC2BP,
  • M2BP,

Description…

LGALS3BP is a secreted protein that binds to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. Elevated levels of LGALS3BP have been found in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV).

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: LGALS3BP

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Under Review

Overview

Average expression of LGALS3BP was significantly higher in epithelial ovarian cancer tumors than any other normal tissue tested.

Performance Comment

LGALS3BP was one of 13 genes out of 50 selected for further validation in PMID:21617380.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.