Early Detection Research Network

MIB1

Aliases:
This biomarker is also known as:
  • Mindbomb Homolog 1 (Drosophila),
  • MIB1,
  • DIP1,
  • ZZANK2,
  • DIP-1,
  • Zinc Finger ZZ Type With Ankyrin Repeat Domain Protein 2,
  • DAPK-Interacting Protein 1,
  • Ubiquitin Ligase Mind Bomb,
  • E3 Ubiquitin-Protein Ligase MIB1,
  • Mindbomb E3 Ubiquitin Protein Ligase 1,

Description…

From NCBI Gene: This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: MIB1

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.