Early Detection Research Network

Ovary

Mesothelin, a cell surface antigen, was isolated using an antibody that reacts with ovarian cancers and mesotheliomas. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers.
http://edrn.jpl.nasa.gov/bmdb/biomarkers/organs/64/82
Under Review
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Of the 28 ovarian cancer biomarkers tested in prediagnostic specimens, from the PLCO, CA125 remains the single best biomarker for ovarian cancer and has its strongest signal within six months of diagnosis. MSLN alone was not a strong predictor.
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