Early Detection Research Network

http://edrn.jpl.nasa.gov/bmdb/biomarkers/organs/20/41/sensitivity-data-3

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The dataset contains the original values and the log transformed values for CA125, CA15.3, CA19.9, CA72.4, KLK6 (aka HK6), HE4, and OV110 (aka B7-H4). Created by Allison Vitonis. Partners used plate-based assay for B7-H4(Diadexus), HE4, and Kallikrein 6 (as described in (Diamandis EP, Scorilas A, Fracchioli S, Van Gramberen M, De Bruijn H, Henrik A, Soosaipillai A, Grass L, Yousef GM, Stenman UH, Massobrio M, Van Der Zee AG, Vergote I, and Katsaros D, Human kallikrein 6 (hK6): a new potential serum biomarker for diagnosis and prognosis of ovarian carcinoma. J Clin Oncol, 2003. 21(6): p. 1035-43)). Platform-based assays (Roche) were used for CA125, CA15.3, CA72.4 and CA19.9. Unless the volume was insufficient assays were run in duplicate and averaged. These seven markers were chosen based on their performance in the phase II (pre-PLCO) data. This data us available in the file entitle "Harvard_markers_11132008.xls" which is linked to this record on the MUC16 Basics Tab.