Early Detection Research Network

NDUFA10

Aliases:
This biomarker is also known as:
  • CI-42k,
  • complex I 42kDa subunit,
  • CI-42kD,
  • Complex I-42kD,
  • NDUFA10,
  • CI-42KD,
  • NADH-ubiquinone oxidoreductase 42 kDa subunit,
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa,
  • NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial,
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD),

Description…

NDUFA10 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Mammalian complex I is the first enzyme complex in the electron transport chain of mitochondria. It is composed of 45 different subunits. This protein is a component of the hydrophobic protein fraction and has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: NDUFA10

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

NDUFA10 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.