Early Detection Research Network

PCCA

Aliases:
This biomarker is also known as:
  • propionyl-CoA carboxylase alpha chain, mitochondrial,
  • PCCase alpha subunit,
  • PCCase subunit alpha,
  • pccA complementation group,
  • PCCA,
  • propionyl Coenzyme A carboxylase, alpha polypeptide,
  • EC 6.4.1.3,
  • Propanoyl-CoA:carbon dioxide ligase subunit alpha,
  • propionyl CoA carboxylase, alpha polypeptide,
  • propanoyl-CoA:carbon dioxide ligase alpha subunit,

Description…

PCCA, or propionyl CoA carboxylase, alpha polypeptide, is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. The beta subunit is PCCB. The enzyme deficiency propionic acidemia results from mutations in either PCCA or PCCB. Several isoforms for this gene have been identified, coded by multiple transcript variants.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: PCCA

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

PCCA was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.