Early Detection Research Network


This biomarker is also known as:
  • propionyl-CoA carboxylase alpha chain, mitochondrial,
  • PCCase alpha subunit,
  • PCCase subunit alpha,
  • pccA complementation group,
  • PCCA,
  • propionyl Coenzyme A carboxylase, alpha polypeptide,
  • EC,
  • Propanoyl-CoA:carbon dioxide ligase subunit alpha,
  • propionyl CoA carboxylase, alpha polypeptide,
  • propanoyl-CoA:carbon dioxide ligase alpha subunit,


PCCA, or propionyl CoA carboxylase, alpha polypeptide, is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. The beta subunit is PCCB. The enzyme deficiency propionic acidemia results from mutations in either PCCA or PCCB. Several isoforms for this gene have been identified, coded by multiple transcript variants.


There are no datasets associated with this biomarker.

QA State: Curated
Type: Protein

The following organs have data associated with this biomarker…


Phase: Two
QA State: Under Review


No additional breast data available.

Performance Comment

PCCA was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.