Early Detection Research Network

Philips VOCs signature

This biomarker is also known as:
  • Philips VOCs signature,


A combination of 22 breath volatile organic compounds (VOCs), predominantly alkanes, alkane derivatives, and benzene derivatives, that can discriminate between patients with and without lung cancer, regardless of stage (all p<0.0003).


There are no datasets associated with this biomarker.

QA State: Curated
HGNC Name:

Panel Details

No member markers defined for this panel.

The following organs have data associated with this biomarker…


Phase: One
QA State: Curated


In patients with an abnormal chest radiograph, a combination of 22 VOCs in breath samples distinguished between patients with and without lung cancer. Prospective studies are needed to confirm the usefulness of breath VOCs for detecting lung cancer in the general population.

Performance Comment

For stage 1 lung cancer, the 22 VOCs had 100% sensitivity and 81.3% specificity. Cross-validation of the combination correctly predicted the diagnosis in 71.7% patients with lung cancer and 66.7% of those without lung cancer.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.

No other associated resources found.