Early Detection Research Network

PNP

Aliases:
This biomarker is also known as:
  • NP,
  • nucleoside phosphorylase,
  • PUNP,
  • MGC125915,
  • PNP,
  • PRO1837,
  • FLJ97288,
  • purine nucleoside phosphorylase,
  • FLJ97312,
  • MGC125916,
  • MGC117396,
  • FLJ94043,

Description…

PNP, a cytoplasmic protein, is an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Defects in PNP are the cause of purine nucleoside phosphorylase deficiency (PNP deficiency) which leads to a severe T-cell immunodeficiency with neurologic disorder in children. PNP mutations also affect B-cell immunity and antibody responses.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: PNP

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.