Early Detection Research Network

POSTN

Aliases:
This biomarker is also known as:
  • PN,
  • periostin, osteoblast specific factor,
  • Osteoblast-specific factor 2,
  • periostin,
  • POSTN,
  • OSF2,
  • OSF-2,

Description…

POSTN, a secreted protein, binds to heparin and induces cell attachment and spreading. It may additionally play a role in cell adhesion and in extracellular matrix mineralization. POSTN is widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. It is up-regulated in epithelial ovarian tumors while not expressed in normal ovaries. POSTN is also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. It is overexpressed in breast cancers.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: POSTN

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.