Early Detection Research Network

PRMT1

Aliases:
This biomarker is also known as:
  • HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2,
  • HCP1,
  • PRMT1,
  • ANM1,
  • Histone-arginine N-methyltransferase PRMT1,
  • HRMT1L2,
  • HMT1 hnRNP methyltransferase-like 2 (S. cerevisiae),
  • IR1B4,
  • HMT2,
  • Protein arginine N-methyltransferase 1,
  • Interferon receptor 1-bound protein 4,

Description…

PRMT1 is an arginine N-methyltransferase that functions as a histone methyltransferase specific for H4. Together with dimethylated PIAS1, it represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. PRMT1 may also be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.PRMT1 is widely expressed.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: PRMT1

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.