Early Detection Research Network

PTPA

Aliases:
This biomarker is also known as:
  • Serine/threonine-protein phosphatase 2A regulatory subunit B',
  • phosphotyrosyl phosphatase activator,
  • PP2A, subunit B', PR53 isoform,
  • protein phosphatase 2A activator, regulatory subunit 4,
  • serine/threonine-protein phosphatase 2A regulatory subunit B',
  • PPP2R4,
  • PP2A,
  • PP2A phosphatase activator,
  • EC 5.2.1.8,
  • PTPA,
  • Serine/threonine-protein phosphatase 2A regulatory subunit 4,
  • PP2A subunit B' isoform PR53,
  • protein phosphatase 2A, regulatory subunit B' (PR 53),
  • Phosphotyrosyl phosphatase activator,
  • PR53,
  • serine/threonine-protein phosphatase 2A activator,

Description…

From NCBI Gene: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: PTPA

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.