Early Detection Research Network


This biomarker is also known as:
  • T200,
  • T200 glycoprotein,
  • GP180,
  • Leukocyte common antigen,
  • T200 leukocyte common antigen,
  • LCA,
  • L-CA,
  • receptor-type tyrosine-protein phosphatase C,
  • CD45R,
  • PTPRC,
  • B220,
  • CD45 antigen,
  • protein tyrosine phosphatase, receptor type, c polypeptide,
  • CD45,
  • EC,
  • LY5,
  • protein tyrosine phosphatase, receptor type, C,


PTPRC is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. PTPRC is required for T-cell activation through the antigen receptor. PTPRC contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and is classified as a receptor type PTP.


There are no datasets associated with this biomarker.

QA State: Curated
Type: Protein

The following organs have data associated with this biomarker…


Phase: Two
QA State: Under Review


No additional breast data available.

Performance Comment

PTPRC was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.