Early Detection Research Network

PTPRN2

Aliases:
This biomarker is also known as:
  • phogrin,
  • IAR,
  • protein tyrosine phosphatase, receptor type, N polypeptide 2,
  • R-PTP-N2,
  • KIAA0387,
  • protein tyrosine phosphatase receptor pi,
  • IAR/receptor-like protein-tyrosine phosphatase,
  • Islet cell autoantigen-related protein,
  • IA-2beta,
  • tyrosine phosphatase IA-2 beta,
  • PTPRN2,
  • receptor-type tyrosine-protein phosphatase N2,
  • ICAAR,

Description…

PTPRN2 is a member of the protein tyrosine phosphatase (PTP) family. These proteins are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a receptor-type PTP. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Gene
HGNC Name: PTPRN2

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.