Early Detection Research Network

SEC23B

Aliases:
This biomarker is also known as:
  • Sec23 homolog B (S. cerevisiae),
  • transport protein SEC23B,
  • CDAN2,
  • protein transport protein Sec23B,
  • HEMPAS,
  • CDA-II,
  • Sec23 (S. cerevisiae) homolog B,
  • SEC23-related protein B,
  • Q15437,
  • CDAII,
  • SEC23B,
  • congenital dyserythropoietic anemia, type II,
  • SEC23-like protein B,

Description…

SEC23B is a member of the SEC23B/SEC24B family. SEC23B is a component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. By similarity, it has been shown that COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: SEC23B

The following organs have data associated with this biomarker…

Attributes

Phase: Two
QA State: Under Review

Overview

No additional ovarian data available.

Performance Comment

SEC23B was one of 50 tumor vasculature-associated genes with transmembrane or secreted protein products identified through expression profiling of ovarian cancer vascular cells. These 50 tumor vascular markers (TVMs) also had low or no expression in normal tissues. SEC23B was not in the group of 13 selected for further validation.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

No associated publications found.