Early Detection Research Network

SERPINA1

Aliases:
This biomarker is also known as:
  • serine (or cysteine) proteinase inhibitor, clade A, member 1,
  • alpha-1-antitrypsin null,
  • Alpha-1-antiproteinase,
  • hAAT,
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1,
  • PRO2275,
  • PI,
  • Serpin A1,
  • protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin,
  • MGC9222,
  • Alpha-1 protease inhibitor,
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1,
  • alpha1AT,
  • MGC23330,
  • A1AT,
  • A1A,
  • AAT,
  • PI1,
  • alpha-1-antitrypsin,

Description…

Alpha-1-antitrypsin is secreted and is an extracellular serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Elevation of alpha1-AT serum levels have been observed in the course of a large number of malignant diseases. Several transcript variants encoding the same protein have been found for this gene.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State 3: Under Review
Type: Protein
Short Name:
HGNC Name 3: SERPINA1

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.