Early Detection Research Network

SLC11A1

Aliases:
This biomarker is also known as:
  • LSH,
  • NRAMP,
  • natural resistance-associated macrophage protein 1,
  • solute carrier family 11 (sodium/phosphate symporters), member 1,
  • NRAMP 1,
  • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1,
  • SLC11A1,
  • NRAMP1,
  • P49279,

Description…

SLC11A1 is a membrane associated divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family. Mutations in the SLC11A1 gene are involved in susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Several alternatively spliced variants have been identified.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: SLC11A1

The following organs have data associated with this biomarker…

Attributes

Phase: One
QA State: Under Review
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.