Early Detection Research Network

SPON2

Aliases:
This biomarker is also known as:
  • FLJ34460,
  • DIL1,
  • FLJ22401,
  • Mindin,
  • Spondin-2,
  • spondin 2, extracellular matrix protein,
  • SPON2,
  • M-spondin,
  • DIL-1,
  • FLJ16313,
  • Differentially expressed in cancerous and non-cancerous lung cells 1,
  • spondin 2,

Description…

SPON2, also known as spondin-2, is a cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. It binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Spondin-2 is essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the extacellular matrix for microbial pathogens. Spondin-2 also binds bacterial lipopolysaccharide.

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Curated
Type: Protein
HGNC Name: SPON2

The following organs have data associated with this biomarker…

Attributes

Phase: Three
QA State: Curated
Organ-specific information for this biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact the Informatics Center if you should have access to this biomarker.