Early Detection Research Network

TEK

Aliases:
This biomarker is also known as:
  • venous malformations, multiple cutaneous and mucosal,
  • soluble TIE2 variant 1,
  • soluble TIE2 variant 2,
  • tunica interna endothelial cell kinase,
  • tyrosine-protein kinase receptor TIE-2,
  • TIE2,
  • endothelial tyrosine kinase,
  • TIE-2,
  • p140 TEK,
  • CD202B,
  • TEK,
  • hTIE2,
  • VMCM1,
  • Tyrosine-protein kinase receptor TIE-2,
  • Tyrosine-protein kinase receptor TEK,
  • TEK tyrosine kinase, endothelial,
  • tyrosine kinase with Ig and EGF homology domains-2,
  • Tunica interna endothelial cell kinase,
  • Tyrosine kinase with Ig and EGF homology domains-2,
  • CD202b antigen,
  • Endothelial tyrosine kinase,
  • VMCM,
  • EC 2.7.10.1,
  • angiopoietin-1 receptor,
  • tyrosine-protein kinase receptor TEK,

Description…

From NCBI Gene: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

Datasets

There are no datasets associated with this biomarker.

Attributes
QA State: Under Review
Type: Protein
HGNC Name: TEK

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.